Dr Valentina Leta

Clinical Research Fellow

Dr Valentina Leta is a Clinical Research Fellow to Professor Chaudhuri at King’s College London and the Parkinson’s Foundation Centre of Excellence, King’s College Hospital, London. She is interested in both motor and non-motor aspects of movement disorders, with a focus on autonomic dysfunction in Parkinson’s disease. Her previous research was focused on biomarkers in movement disorders including the use of skin biopsy in the diagnosis of Parkinson’s disease.

She successfully graduated in Medicine at the University of Bologna (Italy) in 2013 with an awarded thesis entitled ‘Skin nerve α-synuclein deposits: a biomarker for idiopathic Parkinson disease’. She has recently completed her training as a Neurologist at the University of Milan (Italy) with the highest marks and a thesis entitled ‘Intrajejunal levodopa infusion combined with Catechol-O-Methyl Transferase inhibition: a new therapeutic strategy in advanced Parkinson’s disease’.

She is currently working as a Clinical Trials Physician at King’s College Hospital London and starting a PhD under the supervision of Professor Chaudhuri on the gastrointestinal dysfunction in Parkinson’s disease. Valentina is also a member of the International Parkinson and Movement Disorder Society (IPMDS) and one of the coordinators of the IPMDS Non-motor study group.



MD (Italy)

Neurologist (Italy)


Core expertise:

Parkinson’s disease

Non-motor symptoms

Skin biopsy

Movement disorders


Clinical Trials (commercial and non-commercial)


Publication list:

Invernizzi A, Acquistapace A, Bochicchio S, Resnati C, Rusconi S, Ferrari M, Leta V, Pomati S, Klistorner A, Mccluskey P, Staurenghi G, Riva A. Correlation between inner retinal layer thickness and cognitive function in HIV: new insights from an exploratory study. AIDS. 2018 Jul 17;32(11):1485-1490.

Donadio V, Liguori R, Vandi S, Pizza F, Dauvilliers Y, Leta V, Giannoccaro MP, Baruzzi A, Plazzi G. Lower wake resting sympathetic and cardiovascular activities in narcolepsy with cataplexy. Neurology. 2014 Sep 16;83(12):1080-6.

Donadio V, Incensi A, Leta V, Giannoccaro MP, Scaglione C, Martinelli P, Capellari S, Avoni P, Baruzzi A, Liguori R. Skin nerve α-synuclein deposits: a biomarker for idiopathic Parkinson disease. Neurology. 2014 Apr 15;82(15):1362-9.

Donadio V, Liguori R, Vandi S, Giannoccaro MP, Pizza F, Leta V, Plazzi G. Sympathetic and cardiovascular changes during sleep in narcolepsy with cataplexy patients. Sleep Med. 2014 Mar;15(3):315-21.

Di Vito L, de Biase D, Pession A, Visani M, Liguori R, Zambito Marsala S, Leta V, De Carolis P, Donadio V. Brachial amyotrophic diplegia associated with the a140a superoxide dismutase 1 mutation. Neurogenetics. 2013 Nov;14(3-4):255-6.

Leta V, Taddei RN, Sauerbier A, Odin P, Poewe W, van Wamelen DJ, Lim EW, Parry M, Podlewska AM, Hall L, Tentis S, Dubois P, Pantoni L, Chaudhuri KR. Catechol-O-methyl transferase inhibition and intrajejunal levodopa infusion combination therapy in advanced Parkinson’s disease: a real-life experience. In preparation.

Van Wamelen DJ, Podlewska AM, Leta V, Smilowska K, Rizos A, Martinez-Martin P, Bloem BR, Chaudhuri KR. Slave to the rhythm: seasonal differences in non-motor symptoms in Parkinson’s disease. Submitted to Parkinsonism & Related Disorders.

Van Wamelen DJ, Hota S, Podlewska A, Leta V, Trivedi D, Rizos A, Parry M, Chaudhuri KR. Non-motor correlates of wrist-worn wearable sensor use in Parkinson’s disease. Submitted to European Journal of Neurology.